NGS-Based Cancer Sequencing Tools

SeraCare’s clinical genomics technologies enable the promise of precision medicine by helping scientists and clinicians build and implement better assays.

Comprehensive solutions for every phase:

  • Assay Development: Relevant, stable and customizable materials with valuable mutations and variant types

  • Assay Validation: Readily available, patient-like materials to validate your workflow

  • Laboratory QC: Reliable materials that are easy to use, consistent and cost effective


Standards for Liquid Biopsy and Tumor Profiling

Actionable variants to optimize and challenge your assay

  • Expert-designed constructs with a mix of common, rare, and challenging variants
  • Range of variant types includes single nucleotide variants (SNVs), insertion-deletion mutations (INDELs), structural variants (SVs), and fusion RNA transcripts
  • Seraseq biosynthetic technology can precisely modulate allele frequency for accurate assessment of LOD

Patient-like materials to assess entire workflow,

  • Proprietary technology for the most patient-like ctDNA reference materials available
  • FFPE cell lines to monitor and optimize your entire solid tumor assay workflow
  • Expedite development and validation with purified mutation DNA and RNA mixes

Economical, precise, consistent reference material

  • Highly multiplexed material with up to 40 variants in a single sample to maximize data output from each
    sequencing run
  • Digital PCR ensures precise quantitation
  • Manufactured in GMP-compliant and ISO 13485-certified facilities for consistency across time and material
    lots

 

FFPE Product Material Number
  Seraseq™ FFPE Tumor Fusion RNA Reference Material v2 0710 - 0129
  Seraseq™ FFPE Tumor KRAS Reference Material Kit 0710 - 0117
Purified DNA Product Material Number
  Seraseq™ Fusion RNA Mix v2 0710 - 0127
  Seraseq™ Tumor Mutation DNA Mix v2 AF4 LC 0710 - 0070
  Seraseq™ Tumor Mutation DNA Mix v2 AF7 LC 0710 - 0072
  Seraseq™ Tumor Mutation DNA Mix v2 AF10 LC 0710 - 0074
  Seraseq™ Tri-Level Tumor Mutation DNA Mix v2 LC 0710 - 0076
  Seraseq™ Tri-Level Tumor Mutation DNA Mix v2 HC 0710 - 0097
  Seraseq™ Tumor Mutation DNA Mix v2 AF10 HC 0710 - 0094
  Seraseq™ Tumor Mutation DNA Mix v2 AF7 HC 0710 - 0095
  Seraseq™ Tumor Mutation DNA Mix v2 AF4 HC 0710 - 0096

 

Purified CtDNA Product Material Number
  Seraseq™ ctDNA Mutation Mix v2 AF 2% 0710-0139
  Seraseq™ ctDNA Mutation Mix v2 AF 1% 0710-0140
  Seraseq™ ctDNA Mutation Mix v2 AF 0.5% 0710-0141
  Seraseq™ ctDNA Mutation Mix v2 AF 0.25% 0710-0142
  Seraseq™ ctDNA Mutation Mix v2 AF 0.125% 0710-0143
  Seraseq™ ctDNA Mutation Mix v2 WT 0710-0144
Patient-like,  Product Material Number
synthetic plasma Seraseq™ ctDNA Reference Material v2 AF 2% 0710-0203
  Seraseq™ ctDNA Reference Material v2 AF 1% 0710 - 0204
  Seraseq™ ctDNA Reference Material v2 AF 0.5% 0710-0205
  Seraseq™ ctDNA Reference Material v2 AF 0.25% 0710 - 0206
  Seraseq™ ctDNA Reference Material v2 AF 0.125% 0710-0207
  Seraseq™ ctDNA Reference Material v2 WT 0710 - 0208



 For research use only. Not for use in diagnostic procedures 

 

Liquid Biopsy Standards

The most patient-like ctDNA reference materials available

Learn More

Check out our VariantFlex™ Library Custom Services

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