Check out our VariantFlex™ Library Custom Services
SeraCare’s clinical genomics technologies enable the promise of precision medicine by helping scientists and clinicians build and implement better assays.
SeraCare has a wide selection of pathogenic, expert-designed variants and variant types, with patient-like sample performance and precise control over mutation frequencies to properly develop, validate, and monitor inherited disease assays.
Comprehensive Solutions for Every Phase:
Are you looking for a variety of actionable variants not readily available in traditional references such as NA12878 to expedite assay development and validation?
We work with renowned clinical laboratory experts to develop disease-specific standards with clinically relevant variants, such as single nucleotide variants and insertion-deletion (indel) mutations.
Disease specific, actionable variants to challenge your inherited disease test
SeraCare in consultation with clinical laboratory experts has designed actionable (disease-specific) variants including single nucleotide variants (SNVs) and both small and large insertion-deletion mutations (indels) so you don’t have to waste valuable resources and time to identify and source relevant variants.
Multiplexed, economical and consistent reference material
Multiplexing a large number of variants (including SNVs and indels) in a single sample saves $1000’s in sequencing and validation costs relative to evaluating one or few variants at a time. Developed in cGMP-compliant, ISO 13485 certified facilities, Seraseq NGS reference materials provide a consistent source of reference standards.
Customizable format with patient-like sample performance
Using a biosynthetic approach that produces data virtually identical to a patient sample with the same variant, the product can be customized to any target of interest (from either our pre-defined library or user defined) at the desired allele frequency. This is valuable for both assay development and potential use as an external quality assurance (or proficiency testing) sample.
Target genes covered by Seraseq Inherited Disease products: