SARS-CoV-2 Variant Solutions

CLINICAL DIAGNOSTIC QUALITY SOLUTIONS FOR SARS-COV-2 VARIANT ANALYSIS

AccuPlex™ SARS-CoV-2 Variant Panels offer complete SARS-CoV-2 genome coverage with a focus on S-gene mutations (Table 1) in prominent variants of concern (VOC). Each kit has one vial for each included variant as well as a fourth wild type (reference sequence NC_045512) control vial. An RNase P negative control vial is also included.

Product Description Material Number Strain Pack Size Concentration

 

AccuPlex SARS-CoV-2 Variant Panel 1



0505-0241
UK B.1.1.7
S. Africa B.1.351
Brazil P.1
Wuhan Wild Type
RNase P negative

 

  

Positive    4 x 1.5 mL
Negative   1 x 1.5 mL

 

  

Positive 15,000 cp/mL
Negative 5,000 cp/mL

 

AccuPlex SARS-CoV-2 Variant Panel 2

 

0505-0276

Kappa B.1.617
Delta B.1.617.2
Delta Plus AY.1
Wuhan Wild Type
RNase P negative

Not for In Vitro Diagnostic Use. Research Use Only.

SARS-CoV-2 Variant Solution:

  • Performance confirmation of existing SARS-CoV-2 molecular assays with different variants
  • Reference materials for SARS-CoV-2 variant genotyping assays
  • Reference materials for SARS-CoV-2 NGS assays

Table 1: Mutations and variant strains contained in the AccuPlex SARS-CoV-2 Variant Panels

Amino Acid Change

Nucleotide Change

UK B.1.1.7

S. Africa B.1.351

Brazil P.1

Kappa B.1.617

Delta B.1.617.2

Delta Plus AY.1

L18F

C21614T

 

 

X

     

T19R

C21618G

        X X

T20N

C21621A

 

 

X

     

P26S

C21638T

 

 

X

     

HV 69-70 deletion

21765-21770 deletion

X

 

 

     

D80A

A21801C

 

X

 

     

T95I

C21846T

      X X X

Silent

T21895C

      X    

D138Y

G21974T

 

 

X

     

G142D

G21987A

      X X  

Y144 deletion

21991-21993 deletion

X

 

 

     

E154K

G22022A

      X    

E156G

22029-22034 del AGTTCA

        X X

F157 and R158Del

22029-22034 delAGTTCA

        X X

R190S

G22132T

 

 

X

     

D215G

A22206G

 

X

 

     

242_244 DelLAL

22286-22294 Del

 

X

 

     

W258L

G22335T

          X

K417N

G22813T

 

X

 

   

X

K417T

A22812C

 

 

X

     

L452R

T22917G

      X X X

T478K

C22995A

        X X

E484K

G23012A

 

X

X

     

E484Q

G23012C

      X    

N501Y

A23063T

X

X

X

     

A570D

C23271A

X

 

 

     

D614G

A23403G

X

X

X

X

X

X

H655Y

C23525T

 

 

X

     

P681H

C23604A

X

 

 

     

P681R

C23604G

      X X X

A701V

C23664T

 

X

 

     

T716I

C23709T

X

 

 

     

D950N

G24410A

        X X

S982A

T24506G

X

 

 

     

T1027I

C24642T

 

 

X

     

Q1071H

A24775T

      X    

D1118H

G24914C

X

 

 

     

V1176F

G25088T

 

 

X