SARS-CoV-2 Variant Solutions


AccuPlex™  SARS-CoV-2 Variant Reference Materials offer complete SARS-CoV-2 genome coverage with a focus on representative S and N gene mutations (Table 1) in prominent variants of concern (VOC). Each kit has one vial for each included variant, a wild type (reference sequence NC_045512) control vial, and an RNase P negative control vial. 

Product Description Material Number Strain Pack Size Concentration


AccuPlex SARS-CoV-2 Variant Panel 1

UK B.1.1.7
S. Africa B.1.351
Brazil P.1
Wuhan Wild Type
RNase P negative



Positive    4 x 1.5 mL
Negative   1 x 1.5 mL





Positive 15,000 cp/mL
Negative 5,000 cp/mL


AccuPlex SARS-CoV-2 Variant Panel 2



Kappa B.1.617
Delta B.1.617.2
Delta Plus AY.1
Wuhan Wild Type
RNase P negative

AccuPlex SARS-CoV-2 Omicron Reference Material Kit


Omicron B.1.1.529
Wuhan Wild Type
RNase P negative

Positive    2 x 1.5 mL
Negative   1 x 1.5 mL

Not for In Vitro Diagnostic Use. Research Use Only.

SARS-CoV-2 Variant Solution:

  • Performance confirmation of existing SARS-CoV-2 molecular assays with different variants
  • Reference materials for SARS-CoV-2 variant genotyping assays
  • Reference materials for SARS-CoV-2 NGS assays

Table 1: Mutations and variant strains contained in the AccuPlex SARS-CoV-2 Reference Materials

Nucleotide Change Amino Acid Change UK B.1.1.7 S. Africa B.1.351


Kappa B.1.617 Delta B.1.617.2 Delta Plus AY.1 Omicron B.1.1.529
C21614T L18F     X        
C21618G T19R         X X  
C21621A T20N     X        
C21638T P26S     X        
C21762T A67V             X
21765-21770 deletion HV 69-70 deletion X           X
A21801C D80A   X          
C21846T T95I       X X X X
T21895C Silent       X      
G21974T D138Y     X        
G21987A G142D       X X    
21987 - 21995 deletion G142D             X
21991-21993 deletion Y144 deletion X            
G22022A E154K       X      
22029-22034 del AGTTCA E156G         X X  
22029-22034 del AGTTCA F157 and R158Del         X X  
G22132T R190S     X        
22194 - 22196 deletion NL211I             X
A22206G D215G   X          
22205GAGCCAGAAins 215EPEins             X
22286-22294 Del 242_244 DelLAL   X          
G22335T W258L           X  
G22578A G339D             X
TC22673CT S371L             X
T22679C S373P             X
C22686T S375F             X
G22813T K417N   X       X X
A22812C K417T     X        
T22882G N440K             X
G22898A G446S             X
T22917G L452R       X X X  
G22992A S477N             X
C22995A T478K         X X X
G23012A E484K   X X        
G23012C E484Q       X      
A23013C E484A             X
A23040G Q493R             X
G23048A G496S             X
A23055G Q498R             X
A23063T N501Y X X X       X
T23075C Y505H             X
C23202A T547K             X
C23271A A570D X            
A23403G D614G X X X X X X X
C23525T H655Y     X       X
T23599G N679K             X
C23604A P681H X           X
C23604G P681R       X X X  
C23664T A701V   X          
C23709T T716I X            
C23854A N764K             X
G23948T D796Y             X
C24130A N856K             X
G24410A D950N         X X  
A24424T Q954H             X
T24469A N969K             X
C24503T L981F             X
T24506G S982A X            
C24642T T1027I     X        
A24775T Q1071H       X      
G24914C D1118H X            
C25000T D1146D             X
G25088T V1176F     X        
C25584T T64T             X
A28271T n/a             X
C28311T P13L             X
28362 - 28370 deletion ERS31del             X
G28881A, G28882A, G28883C RG203KR             X