Seraseq™ Aneuploidy Negative (Euploid) Reference Material
Seraseq Aneuploidy Negative (Euploid) Reference Material is a full-process negative reference material for NGS based non-invasive prenatal testing (NIPT) assays designed to detect common trisomies such as trisomy 21, 18, and 13 in cell-free DNA (cfDNA) circulating in the maternal bloodstream. This product provides clinical labs and assay developers with consistent, readily available reference material for assay development, validation, run monitoring, and troubleshooting.
Confirmed euploid DNA
Male fetal DNA is a confirmed euploid sample (derived from PBMC). Maternal DNA is unrelated and obtained from non-pregnant female DNA (euploid).
Size distribution profile similar to authentic cell-free DNA
DNA is fragmented to ~170bp to mimic cfDNA sizing for simplified library preparation.
Precisely tuned fetal fraction amount
Precise formulation and digital PCR quantitation of fetal fraction.
Biosynthetic DNA mixture is stabilized, encapsulated, and introduced into plasma-like matrix material
Supports maximum commutability; behaves like a true clinical sample and follows identical process workflow from extraction through data analysis.
Reproducible, consistent production process
Highly characterized manufacturing process in cGMP compliant, ISO-9001, and ISO 13485-certified facilities.
For research use only. Not for use in diagnostic procedures.