Controls & Reference Materials

Seraseq® Tri-Level Tumor Mutation DNA Mix v2 LC

Material Number 0710-0076
Size 1 x 25 µL
Inventory Status In Stock
Unit EA

The Seraseq Tri-Level Tumor Mutation DNA Mix v2 (LC) is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices, offered in a high concentration (LC) format at 5 ng/µL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product offers a range of allele frequencies in a single sample format, including single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).

  • Single-sample format for daily run use
  • 40 unique multiplexed variants across 28 genes (see table in Specifications tab) at allele frequencies distributed at 4%, 7% or 10%
    • 20 SNVs
    • 5 SNVs that are part of homopolymers
    • 13 indels
    • 2 SVs
  • Mutation targets quantitated with digital PCR
  • Well-characterized GM24385 human genomic DNA as background ‘wild-type’ material
  • Manufactured under cGMP within ISO 9001 and ISO 13485 certified facilities

The Seraseq Tri-Level Tumor Mutation DNA Mix v2 (HC) is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tri-Level Mutation DNA Mix v2 (HC) is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters.

For research use only. Not for use in diagnostic procedures.

Seraseq Solid Tumor Mutation Ladder-II LC

Doc type
Package Insert

Seraseq Tri-Level Tumor Mutation DNA Mix v2 High Concentration (HC)

Doc type
Product Sheet

Seraseq Tri Level Tumor Mutation DNA Mix v2 Low Concentration (LC)

Doc type
Product Sheet
Lot #
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Gene List

AKTI FGFR3 JAK2 PDGFRA
APC FLT3 KIT PIK3CA
ATM FOXL2 KRAS PTEN
BRAF GNA11 MPL RET
CTNNB1 GNAQ NCOA4-RET SMAD4
EGFR GNAS NPM1 TP53
ERBB2 IDH1 NRAS/CSDE1 TPR-ALK