Seraseq Cardiomyopathy Reference Material addresses the lack of multiplexed, patient-like reference materials with an expert-designed product1 for targeted NGS assays focused on hypertrophic cardiomyopathy (HCM). This unique product combines ten actionable HCM mutations in a well-characterized genomic background and can be used for assay development, validation, and to support lab QC standardization.
Key features include:
Ten variants considered pathogenic or likely pathogenic for HCM in a single sample
Mutation targets precisely quantitated with digital PCR
Well-characterized GM24385 human genomic DNA as background wild-type material
Manufactured in cGMP compliant and ISO 13485-certified facilities
1. Emily M Kudalkar, Naif AM Almontarishi, Catherine Huang, Bharathi Anekella, Mark Bowser, Elizabeth Hynes, Russell Garlick, Birgit H. Funke. Multiplexed reference materials as controls for diagnostic next generation sequencing – a pilot investigating applications for hypertrophic cardiomyopathy, The Journal of Molecular Diagnostics.
For research use only. Not for use in diagnostic procedures.