New ctDNA reference materials for NGS

May 18, 2018 - SeraCare Life Sciences is adding ct­DNA Complete and ctDNA Panels to its circulating tumor DNA portfolio of reference materials. These new materials expand the Seraseq product line to also cover copy number variations and accelerate single-gene and variant-focused testing.

Seraseq ctDNA Complete is an expert-curated content that adds broader coverage of all genomic events, including SNVs, indels, CNVs, and structural rearrangements. Seraseq ctDNA Panels are disease-focused, low-plex reference samples of clinically relevant driver mutations in oncogenes implicated in lung cancer. These include driver mutations in EGFR (T790M, L858R, exon 19 deletions, G719S), KRAS (G12D), and BRAF (V600E). These oncogenic mutations can be assayed at a limit of detection of 0.1 percent allele frequency against a background of well-characterized genomic background wild-type cell line.

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