To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.
This specific ctDNA Reference Material v2 product is the wild-type with an allele frequency of 0%.
Size distribution, library yield and complexity consistent with native ctDNA
Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
Offered in a full-process plasma-like material capable of assessing the entire workflow from extraction through analysis
Mutation targets precisely quantitated with digital PCR
Single well-characterized GM24385 human genomic DNA as background wild-type material
Manufactured in GMP-compliant and ISO 13485-certified facilities
Seraseq ctDNA Reference Material v2 Wild-Type (WT)
Archer® is a registered trademark, and Reveal ctDNA™ is a trademark of ArcherDx, Inc. Oncomine® is a registered trademark of Thermo Fisher Scientific. UltraSEEK™ is a trademark of Agena Bioscience, Inc.