Liquid Biopsy
Seraseq® ctDNA Mutation Mix v2 AF2%
Material Number
0710-0139
Size
1 x 25 µL
Inventory Status
In Stock
Unit
EA
Details
Resources
Specifications
Frequently Asked Questions
To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.
This specific ctDNA Mutation Mix v2 product has an allele frequency of 2%.
- Size distribution, library yield and complexity consistent with native ctDNA
- Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
- Offered as a purified DNA mixture for ease of use during assay development
- Mutation targets precisely quantitated with digital PCR
- Single well-characterized GM24385 human genomic DNA as background wild-type material
- Manufactured in GMP-compliant and ISO 13485-certified facilities
Seraseq ctDNA Mutation Mix v2
Doc type
Package Insert
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SeraSeq ctDNA Mutation Mix v2 AF2%
Seraseq ctDNA Mutation Mix v2 AF2%
Seraseq ctDNA v2 Reference Materials Product Sheet
Doc type
Product Sheet
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Seraseq ctDNA Mutation Mix v2 AF2%
Seraseq ctDNA Mutation Mix v2 AF2%
Seraseq ctDNA Mutation Mix v2 AF2%
SeraSeq Mutation Mix Non-Requirement Letter
Doc type
Safety Data Sheet (Non-Requirement Letter)
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SeraSeq ctDNA Mutation Mix v2 AF2%
Doc type
Safety Data Sheet (Non-Requirement Letter)
Download
Seraseq ctDNA Mutation Mix v2 AF2%
Technical Spreadsheet for Seraseq ctDNA v2 Mutation Mix and Reference Material
Doc type
Technical Spreadsheet
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Seraseq ctDNA Mutation Mix v2 AF2%
Product Specifications | |
# of Variants | 40 |
Allele Frequency | 2% |
Fragment Size | ~170bp |
Concentration | 10 ng/µL |
Fill Size | 25 µL |
Total DNA | 250 ng |
Buffer | Tris/EDTA (TE) |
NGS-Based Assay Compatibility Chart | |||||
Archer® Reveal ctDNA™ 28 Kit | Oncomine® Pan- Cancer Cell-Free Assay |
Oncomine Lung cfDNA Assay |
Oncomine Colon cfDNA |
UltraSEEK™ Colon Panel |
UltraSEEK Lung Panel |
AKT1 | AKT1 | ALK | AKT1 | BRAF | BRAF |
ALK | ALK | BRAF | BRAF | EGFR | EGFR |
BRAF | APC | EGFR | EGFR | KRAS | ERBB2 |
CTNNB1 | BRAF | ERBB2 | ERBB2 | NRAS | KRAS |
EGFR | CTNNB1 | KRAS | KRAS | PIK3CA | PIK3CA |
ERBB2 | EGFR | NRAS | NRAS | ||
IDH1 | ERBB2 | PIK3CA | PIK3CA | ||
KIT | FGFR3 | ROS1 | SMAD4 | ||
KRAS | FLT3 | TP53 | TP53 | ||
NRAS | GNA11 | ||||
PDGFRA | GNAQ | ||||
PIK3CA | GNAS | ||||
RET | IDH1 | ||||
ROS1 | KIT | ||||
SMAD4 | KRAS | ||||
TP53 | NRAS | ||||
PDGFRA | |||||
PIK3CA | |||||
PTEN | |||||
TP53 | |||||
ROS1 | |||||
RET | |||||
Archer® is a registered trademark, and Reveal ctDNA™ is a trademark of ArcherDx, Inc. Oncomine® is a registered trademark of Thermo Fisher Scientific. UltraSEEK™ is a trademark of Agena Bioscience, Inc. |
Find more data and in-depth technical information by reading this technical product report.
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