Controls & Reference Materials

Seraseq™ ctDNA Mutation Mix v2 AF 0.125%

Material Number 0710-0143
Size 1 x 25 µL
Inventory Status In Stock
Unit EA

To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.

This specific ctDNA Mutation Mix v2 product has an allele frequency of 0.125%.

  • Size distribution, library yield and complexity consistent with native ctDNA
  • Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
  • Offered as a purified DNA mixture for ease of use during assay development
  • Mutation targets precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant and ISO 13485-certified facilities

Seraseq ctDNA v2 Reference Materials

Doc type
Product Sheet

Seraseq ctDNA Mutation Mix v2 AF0.125%

Doc type
Product Report
Lot #

Seraseq ctDNA Mutation Mix v2

Doc type
Package Insert
# of variants: 40
Allele Frequency: 0.125%
Fragment Size: 170bp average
Concentration: 10 ng/µL  
Amount: 250 ng (single vial)
Buffer 1 mM Tris / 0.1 mM EDTA pH 8.0