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Controls & Reference Materials

Seraseq™ ctDNA Complete™ Reference Material WT (0%)

Material Number 0710-0674
Size 1 x 25 µL
Inventory Status In Stock
Unit EA

To further accelerate the validation and clinical application of liquid biopsy-based ccfDNA targeted NGS assays, SeraCare has developed the Seraseq ctDNA Complete((TM) that expands coverage of all relevant variant types (SNVs, INDELs, CNVs, and gene fusions) in a single, highly multiplexed reference sample. These new products are offered in either a purified ctDNA format or a plasma-like matrix format, all precisely quantitated by digital PCR against a single well-characterized genomic background (GM24385), and orthogonally validated with NGS technology.

This specific ctDNA Complete product has an allele frequency of 0%.

  • 25 unique multiplexed variants in 16 genes, covering 12 SNVs, 7 INDELs, 3 CNVs, and 3 SVs, in purified and plasma-like matrix formats
  • 6 different allele frequencies (AF) – WT, 0.1%, 0.5%, 1%, 2.5% and 5%
  • Allows end-to-end evaluation of assay performance across the entire workflow, including pre-analytic extraction steps
  • Variants quantitated with digital PCR and orthogonally validated by NGS
  • Blends with well-characterized GM24385 human genomic DNA as background ‘wild-type’ material
  • Manufactured within cGMP compliant, ISO 9001 and ISO 13485 certified facilities

Seraseq ctDNA Complete Reference Material (AF5%, AF2.5%, AF1%, AF0.5%, AF0.1%, WT)

Doc type
Package Insert

Seraseq ctDNA Complete Reference Materials

Doc type
Product Sheet

Seraseq ctDNA Complete Reference Material WT

Doc type
Product Report
Lot #
10346910
# of variants: 25
Allele Frequency: WT
Fragment Size: 170bp average
Concentration: 10 ng/µL
Amount: 250 ng (single vial)
Buffer 1 mM Tris / 0.1 mM EDTA pH 8.0

Find more data and in-depth technical information by reading this Technical Product Report.