This white paper addresses the challenges of the analytical validation of liquid biopsy-based MRD assays that allow for the assessment of sensitivity and specificity at variant allele frequencies (VAFs) that can be over an order of magnitude below the typical limit of detection of standard ctDNA assays.
Non-invasive prenatal testing (NIPT) and Preimplantation genetic testing (PGT) continues to expand globally, driven by rapid technological improvements in next-generation sequencing (NGS) methodologies and changes in test reimbursement, resulting in higher test volumes and expanding regulatory oversight. Download this white paper to learn how to get the most out of the Seraseq® Reproductive Health Reference Materials.
This guide contains best practices to help you develop an NGS-based clinical genomics assay and bring it online quickly and cost-effectively. It discusses specific ways to overcome the top three assay development challenges faced by clinical laboratories.
A practical guide focuses on the validation process for NGS-based assays and will walk through key considerations and guidelines you can follow to ensure a smooth and successful validation.
Whatever practices you use for NGS assay development, validation, and performance monitoring, your goal is the same: Your results must be as accurate, precise, and consistent as possible.
AccuPlex Technology for Rapid Development of Molecular Diagnostic Assays in Response to Viral Infectious Diseases
This white paper details how AccuPlexTM recombinant virus technology enables replication-defective virus particles that are commutable in any sample matrix and closely mimic pathogenic virus found in clinical samples.
Comparison of the KPL BacTrace Anti-Salmonella CSA-Plus Antibody to Two Other Anti‑Salmonella Species Antibodies in an Indirect ELISA
Learn why KPL BacTrace antibodies outperform both polyclonal and monoclonal antibodies in an indirect ELISA, and how we achieve the broad reactivity of a polyclonal antibody combined with the specificity of a monoclonal antibody.
Clinical testing labs thrive on consistency, predictability, and efficiency. Lab directors endeavor to establish a steady rhythm of receiving samples, running tests, and reporting results accurately. This is how trust is earned and maintained with clinicians. It’s also how resources – people, equipment, and budgets – are maximized.