Flexible Tools for the Development and Performance Verification
of Customized Target Enrichment Panels
Implementation of next generation sequencing for variant identification and discovery presents difficulties both in the selection of genomic loci for inclusion in a panel, as well as the ability to effectively verify the performance of the assay based on the content selected.
Balancing the relevance of genomic content with the practical hurdles of developing specific assays necessitates new approaches for the application of next generation sequencing toward precision medicine that are aimed at providing the flexibility of content to efficiently provide data capable of testing fundamental biological hypotheses.
Download this poster to see how coupling NEBNext Direct target enrichment with customized SeraCare VariantFlex reference materials containing the indels of interest, enables assessment of panel sensitivity and required DNA inputs for reliable indel detection.
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