1600-0098

Seraseq™ Solid Tumor Mutation Mix-I (AF20)

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  • Size

    1 × 25 μL

  • List Price

    Contact Us

  • Unit

    KIT

  • Inventory Status

    In Stock

Description

Seraseq Solid Tumor Mutation Mix-I (AF20) is a highly multiplexed synthetic DNA mixed with well-characterized genomic background for assessing the overall performance of a somatic mutation assay by next-generation sequencing.

  • 26 unique variants including SNVs, SNVs as part of homopolymer tracts, deletions and insertions
  • Synthetic variants quantitated with droplet digital PCR
  • 20% allele-frequency ratio with GM24385 human genomic DNA as background material
  • 6 base-pair synthetic Internal Quality Marker inserted within 25 base-pairs of variant guards against potential amplicon contamination, simplifies analysis
  • Eliminates the need to obtain, characterize, blend and document mixes of cell lineages
  • Manufactured in cGMP compliant, ISO 9001 and ISO 13485 certified facilities 

By providing well-characterized DNA reference materials, SeraCare offers a precisely quantitated and well-defined mixture of mutations at a defined minor allele frequency for routine use. While assay specific variation does occur, use of a sample control gives assurance in the ability to correctly call different types of mutations.