Novel reference materials for the analysis of methylation in liquid biopsies

Methylation is an important epigenetic modification that influences cellular differentiation and gene expression. Recently, liquid biopsies have started to incorporate analyses of epigenetic modifications for screening purposes to detect cancer-derived DNA in the blood, but obtaining enough ccfDNA for assay development, validation, and proficiency testing is difficult. Download this poster presented at AACR 2022 to see how Seraseq reference materials have been developed to address the challenges associated with assessing the methylation of ccfDNA.