Controls & Reference Materials

Seraseq™ ctDNA Reference Material v2 AF0.25%

Material Number 0710-0206
Size 1 x 5 mL
Inventory Status In Stock
Unit EA

To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.

This specific ctDNA Reference Material v2 product has an allele frequency of 0.25%.

  • Size distribution, library yield and complexity consistent with native ctDNA
  • Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
  • Offered in a full-process plasma-like material capable of assessing the entire workflow from extraction through analysis
  • Mutation targets precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant and ISO 13485-certified facilities

Seraseq ctDNA v2 Reference Materials

Doc type
Product Sheet

Seraseq ctDNA Reference Material v2 AF0.25%

Doc type
Product Report
Lot #
10282171

Seraseq ctDNA Reference Material v2

Doc type
Package Insert
# of variants: 40
Allele Frequency: 0.25%
Fragment Size: 170bp average (and encapsulated)
Concentration: 25 ng/ml
Amount: 125 ng (single vial)
Matrix SeraCon™ Matribase (human plasma-like matrix)