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Controls & Reference Materials

Seraseq™ ctDNA EGFR T790M Mutation Mix AF1%

Material Number 0710-0706
Size 1 x 20 uL
Inventory Status In Stock
Unit EA

Driver mutations in the EGFR, BRAF and KRAS genes represent a combined ~60% of all genomic variants driving oncogenesis of many solid tumor diseases, especially lung cancer. SeraCare is expanding its liquid biopsy portfolio with the addition of low-plex (single-gene) reference materials for clinically-validated biomarkers in these genes as ground-truth standards for molecular testing of circulating tumor DNA patient samples by PCR or NGS technologies. These products are designed for the purpose of validation and standardization of clinical testing of these biomarkers in CLIA/CAP-accredited laboratory developed tests (LDTs), starting with the EGFR T790M variant.

This specific Seraseq ctDNA EGFR T790M product has an allele frequency of 0.1%.

  • Size distribution similar to native ctDNA
  • Offered as a purified DNA mixture for ease of use during processing
  • Mutation precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant and ISO 13485-certified facilities

Seraseq ctDNA EGFR T790M Mutation Mix AF1% & AF0.1%

Doc type
Package Insert

Seraseq ctDNA EGFR T790M Mutation Mix AF1%

Doc type
Product Report
Lot #
10356350

Product Specifications

# of variants 1
Allele Frequency 1%
Fragment Size ~170bp
Concentration 10 ng/µL
Fill Size 20 µL
Total DNA 200 ng
Buffer Tris/EDTA (TE)