Controls & Reference Materials

Seraseq® Tumor Mutation DNA Mix v2 AF 7 HC

Material Number 0710-0095
Size 1 x 25 µL
Inventory Status In Stock
Unit EA

The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).

  • Single-vial format for daily run use
  • 40 unique multiplexed variants across 28 genes (see table in Specifications tab)
    • 20 SNVs
    • 5 SNVs that are part of homopolymers
    • 13 indels
    • 2 SVs
  • Mutation targets quantitated with digital PCR
  • Well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured within cGMP-compliant, ISO 13485-certified facilities

The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters. Previous Part Number: 0710-0073.

For research use only. Not for use in diagnostic procedures.

Seraseq Tumor Mutation DNA Mix v2 AF7, RUO

Doc type
Certificate of Analysis
Lot #
10219422

Seraseq Tumor Mutation DNA Mix v2

Doc type
Product Sheet
Lot #
-

Seraseq Tumor Mutation DNA Mix v2 (HC)

Doc type
Product Sheet
Lot #
-
AKTI FGFR3 JAK2 PDGFRA
APC FLT3 KIT PIK3CA
ATM FOXL2 KRAS PTEN
BRAF GNA11 MPL RET
CTNNB1 GNAQ NCOA4-RET SMAD4
EGFR GNAS NPM1 TP53
ERBB2 IDH1 NRAS/CSDE1 TPR-ALK