Controls & Reference Materials

Seraseq™ Tumor Mutation DNA Mix v2 AF 10 HC

Material Number 0710-0094
Size 1 x 25 µL
Inventory Status In Stock
Unit EA

The Seraseq Tumor Mutation DNA Mix v2 (AF10) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 10%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).

  • Single-vial format for daily run use
  • 40 unique multiplexed variants across 28 genes (see table in Specifications tab)
    • 20 SNVs
    • 5 SNVs that are part of homopolymers
    • 13 indels
    • 2 SVs
  • Mutation targets quantitated with digital PCR
  • Well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured within cGMP-compliant, ISO 13485-certified facilities

The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters.

For research use only. Not for use in diagnostic procedures.

Seraseq Tumor Mutation DNA Mix v2 (HC)

Doc type
Product Sheet

Seraseq Tri-Level Tumor Mutation DNA Mix v2 High Concentration (HC)

Doc type
Product Sheet
AKTI FGFR3 JAK2 PDGFRA
APC FLT3 KIT PIK3CA
ATM FOXL2 KRAS PTEN
BRAF GNA11 MPL RET
CTNNB1 GNAQ NCOA4-RET SMAD4
EGFR GNAS NPM1 TP53
ERBB2 IDH1 NRAS/CSDE1 TPR-ALK