Neurotrophic tyrosine receptor kinases (NTRK) can become abnormally fused to other genes resulting in growth signals that can lead to cancer in many organs of the human body. Anti-tumor drugs that target NTRK fusions have been shown to be largely effective across many tumor types regardless of patient age (adult or pediatric), especially in locally advanced or metastatic solid tumors. This product expands SeraCare's RNA Fusion FFPE reference material product portfolio to support routine clinical diagnostic / companion diagnostic (CDx) use for solid tumor testing of tissue biopsies for NTRK fusion genes in cancer disease diagnosis and treatment selection.
15 clinically-relevant NTRK fusion genes in a single reference sample
Offered as FFPE for full process assay (NGS or PCR) workflow monitoring and patient testing
Fusions precisely quantitated with digital PCR
Well-characterized GM24385 human genomic RNA as background wild-type material
Manufactured in GMP-compliant and ISO 13485-certified facilities
Technical Spreadsheet for Seraseq® FFPE NTRK Fusion RNA Reference Material