SARS-CoV-2 Molecular Solutions

FULL GENOME COVERAGE NOW AVAILABLE

AccuPlex™ SARS-CoV-2 Verification Panel, coupled with the AccuPlex™ SARS-CoV-2 Reference Material, is a complete Quality Solution designed to challenge the entire molecular test procedure ensuring clinical laboratories can have confidence in their SARS-CoV-2 assay results.

AccuPlex™ SARS-CoV-2 Verification Panel is optimized for assay verification at installation by documenting test performance along the assay’s range enabling laboratories to establish lower limits of detection, perform assay comparisons, and evaluate staff proficiency. The product contains positive materials including the full SARS-CoV-2 viral genome, and negative materials targeting the human RNase P gene.

Product Description

Material Number

Region

Pack Size

Concentration


AccuPlex
TM SARS-CoV-2
Verification Panel

 

0505-0168

 

Full Genome

Positive 1
Positive 2
Positive 3
Negative

1 x 3 mL
1 x 3 mL
1 x 3 mL
1 x 3 mL

100,000 copies/mL
10,000 copies/mL
1,000 copies/mL
5,000 copies/mL


AccuPlex™ SARS-CoV-2 Reference Material
is designed to measure day-to-day performance of the assay, providing both a positive and a negative reference solution.
 The product is available in versions that offer different SARS-CoV-2 sequence coverage: Version 1 covers the CDC and WHO consensus sequences, Version 2 has been enhanced to also include the S gene region, and Version 3 is expanded to include the full SARS‐CoV‐2 viral genome (Table 1). All products also include negative reference materials targeting the human RNase P gene.

Product Description

Material Numbers

Region

Pack Size

Concentration


AccuPlex
TM SARS-CoV-2
Reference Material Kit

0505-0126

ORF1a, RdRp, E, N


Positive 5 x 1.5 mL
Negative 5 x 1.5 mL

5,000 copies/mL
5,000 copies/mL (RNase P gene)

0505-0133

ORF1a, RdRp, E, N, S

0505-0159

Full Genome

Click here for bulk quantities or custom requests

Click here to learn more about SARS-CoV-2 Serology Solutions.

SARS-CoV-2 Quality Solutions:

  • Non-infectious and replication deficient, enables safe handling in contrast to viral samples
  • Fully-extractable with a real viral protein coat; superior to “naked” transcribed RNA
  • Compatible with assays targeting CDC and WHO consensus sequences (Table 1)
  • Includes negative reference material for targeting sequences for the human RNAse P gene
  • 2 year stability at 2 - 8°C
  • Customizable to sequences of interest to meet unique assay design requirements
Table 1: Regions included in AccuPlex Coronavirus (SARS-CoV-2) Positive Reference MaterialSARS-CoV-2 Region TableNumbers refer to sequence of GenBank NC_045512.2
Not for In Vitro Diagnostic Use. Research Use Only.
 

LGC SeraCare’s AccuPlex recombinant material serves as a true full process molecular control for your diagnostic assays. Compatible with multiplexed RT-PCR and NGS-based assays, AccuPlex custom recombinant materials are constructed with a replication-deficient mammalian virus, producing a safe, non-infectious material (Figure 1 ). With a protein coat and lipid bilayer, these mammalian virus-based reference materials resemble the complexity of virus targets found in true patient samples.

 AccuPlex Virus Technology Pic

FIGURE 1: 1) RNA sequence from the pathogenic virus of interest is chosen. 2) DNA synthesis and cloning occur to produce the recombinant RNA. 3) Recombinant RNA and helper RNA are co-transfected into the mammalian cells, allowing the encapsulation of recombined RNA. 4) Exocytosis of the mature enveloped non-infectious and replication deficient RNA virus containing the assay target RNA sequence of interest.

 

 

biosearch technologies 

 
 

LGC, Biosearch Technologies Probes and Primers for SARS-CoV-2
Commercially available probe and primer kits released for distribution by CDC testing results.  Additional probes and primers following other protocols published by WHO are also available.

Product Description

Catalog Number

Size

2019-nCoV CDC-qualified Probe and Primer Kits for SARS-CoV-2

KIT-NCOV-PP1-1000

1000 rxns

US CDC 2019-nCoV ValuPanel Reagents*

Multiple catalog numbers for N1. N2, N3 and RNase P

10,000-100,000 rxns

Charité 2019-nCoV BBQ-650 ValuPanel Reagents*

Multiple catalog numbers for RdRP and E Sarbeco

1,000-100,000 rxns

Charité 2019-nCoV BHQ ValuPanel Reagents*

Multiple catalog numbers for RdRP and E Sarbeco

1,000-100,000 rxns

*For Research Use Only.  Not for use in diagnostic procedures. 

 

LGC, Biosearch Technologies RT-PCR Reagents for SARS-CoV-2
High-performing, lyo-compatible master mix for sensitive pathogen detection and an optimized reverse transcriptase system for the production of full-length cDNA.

Product Description

Catalog Number

Size

EpiScript™ RNase H- Reverse Transcriptase*

ERT12910K
ERT12925K

10,000 Units
25,000 Units

RapiDxFire qPCR 5X Master Mix GF*

30050-1
30050-2

1 mL
10 mL

*For Research Use Only.  Not for use in diagnostic procedures.