0710-0077

Seraseq™ Tri-Level Tumor Mutation DNA Mix v2 HC

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  • Size

    1 × 25 µL

  • List Price

    Contact Us

  • Unit

    EA

  • Inventory Status

    In Stock

Description

The Seraseq Tri-Level Tumor Mutation DNA Mix v2 (HC) is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background to a high concentration (HC) at 25 ng/μL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product offers a range of allele frequencies in a single sample format, including single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs). 

  • Single-sample format for daily run use
  • 40 unique multiplexed variants across 28 genes (see table on right) at allele frequencies distributed at 4%, 7% or 10%
    • 20 SNVs
    • 5 SNVs that are part of homopolymers
    • 13 indels
    • 2 SVs 
  • Mutation targets quantitated with digital PCR
  • Well-characterized GM24385 human genomic DNA as background ‘wild-type’ material
  • Manufactured in cGMP compliant, ISO 9001 and ISO 13485 certified facilities


View the Product Sheet
 for a detailed list of variants. 

The Seraseq Tri-Level Tumor Mutation DNA Mix v2 (HC) is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tri-Level Mutation DNA Mix v2 (HC) is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters.

For research use only. Not for use in diagnostic procedures.